Saving a person's life could be as simple as starting a conversation about mental health.
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And Thursday's R U OK? Day is a perfect opportunity to spark those chats, suicide prevention charity chief Katherine Newton said.
She's encouraging people to reach out to those who may be struggling in a move that might be life changing.
"It absolutely does make a difference," Ms Newton told AAP.
"You don't need to be an expert but letting someone be heard and being present with someone can help."
If you notice changes in a friend, family member or colleague's behaviour, asking them how they are and letting them know you're there for support was important.
"Even if they are saying 'I'm fine,' just point out the changes you may have noticed ... and maybe see if there's someone else they would be willing to speak to if not yourself," Ms Newton said.
Events will be held across the country on the national day of action to remind everyone to ask those around them "are you ok?".
Lifeline 13 11 14
beyondblue 1300 22 4636
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Australian Associated Press