Crown Resorts issued a statement on Monday saying his resignation would "take place with immediate effect".

The Perth-based director of the embattled Crown empire has been under pressure to quit since the NSW Liquor and Gaming Authority released a scathing independent report last month saying the company was not suitable to hold a licence for its Sydney casino at Barangaroo.

Crown's executive chairman Helen Coonan said Mr Poynton had been a board member since November 2018 and a director of Crown Perth since 2004.

"During that time, he has been enormously committed as a director, chairman of Crown Perth and through his service on board committees.

"The Independent Liquor and Gaming Authority has advised Crown that it considers it appropriate that John step down as a director of all companies within the Crown group, due to a perceived lack of independence arising out of his past relationship with Mr James Packer and CPH, notwithstanding the recent termination of John's consultancy arrangement with CPH," the statement said.

"As a result, John has agreed to resign in the best interests of Crown and our shareholders, despite no adverse findings by the Commissioner in the ILGA Inquiry in relation to his suitability, integrity or performance.

"On behalf of the board, I thank John for his contribution to Crown over many years," Ms Coonan said.

Mr Packer's private company Consolidated Press Holdings has a 37 per cent share in Crown.

Last week the Victorian government announced a royal commission into Crown.

Crown's chief executive Ken Barton resigned after Patricia Bergin's damning report into Crown and was replaced by Ms Coonan.

Australian Associated Press