The 27-year-old was arrested at about 2am on Monday after police responded to reports of a disturbance on Marshall St.

He is facing three counts of assault causing bodily harm and one count of wilful damage.

Milford was given police bail and is due to make his first appearance in the Brisbane Magistrates Court on October 20.

The Broncos confirmed he has completed his contractual duties with the club in a statement on Monday.

"He is on leave and due to begin a new NRL contract elsewhere at the commencement of the 2022 pre-season," it said.

"As the matter is now before the courts, the Broncos will make no further comment."

The NRL has also confirmed it is aware of the alleged incident and the Integrity Unit is liaising with Queensland Police.

It comes at the end of a horror year for Milford, who was dropped by the Broncos in round 12 and later told his $1 million-a-year deal would not be extended.

After arriving at the Broncos as one of the league's best young talents in 2015, he was their best on field in their golden-point grand final loss that year.

But his form has dwindled ever since Ben Hunt left the NRL club at the end of 2017, before finding himself well out of the picture in recent years.

The former Queensland State of Origin five-eighth was picked for just 13 games this year, while he will likely only play a bench role in his one-year deal at South Sydney.

Australian Associated Press