Police said the 32-year-old woman was confronted by two men at a home on Buchan Avenue at Singleton just after midnight on April 21.

The men - who had their faces concealed - allegedly threatened the woman with a knife and assaulted her, causing her to lose consciousness, before sexually assaulting her.

Emergency services were contacted after the pair fled and officers from Hunter Valley Police District attended, established a crime scene and commenced an investigation.

The woman was taken to John Hunter Hospital for treatment.

Strike Force Currikee has been established by detectives from the State Crime Command's Child Abuse and Sex Crimes Squad and Hunter Valley Police District as inquiries into the incident continue.

Detectives are appealing for anyone with information, or who may have witnessed suspicious activity in the area during that evening or in the days prior, to come forward.

The men were both wearing dark clothing and had their faces concealed, however one man has been described as being of a large build and the other is of a thin build.

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